Now Is The Time For You To Know The Truth About Epistaxis Nursing Assessment. | epistaxis nursing assessment

December 13, 2011

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Celgene International Sàrl, a accessory of Celgene Corporation (NASDAQ: CELG), today appear final after-effects from the appearance II allocation of a multi-center appearance I/II abstraction evaluating aggregate analysis with REVLIMID (lenalidomide) and VIDAZA (azacitidine) in patients with higher-risk myelodysplastic syndromes (MDS) not ahead advised with either drug. These abstracts were presented at the 53rd Annual Meeting of the American Society of Hematology in San Diego, CA.

At a average aftereffect of 15 months and a average of bristles cycles of therapy, the all-embracing acknowledgment amount for 35 evaluable patients was 72%, with 15 patients (42%) accomplishing a complete acknowledgment and 11 (28%) accomplishing hematologic improvement. Three patients had accelerating ache while on therapy. The average continuance of complete acknowledgment at aftermost abstraction appraisal was 16 months (range, 3-36) and average all-embracing adaptation for patients accomplishing a complete acknowledgment was 27 months (range, 7-55). Seven (50%) complete responders progressed to AML at a average of 20 months from accomplishing complete response.

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Grade 3/4 non-hematologic adverse contest (AEs) (related or unrelated) included cardiac (11%), delirious neutropenia (31%), added infection (8%), pulmonary (11%), vascular access-related occlusion (6%), CNS drain (6%) or added (11%). Three (8%) patients died while on study. Average decreases from baseline in complete neutrophil calculation (ANC) and platelets were 35% and 18%, respectively, aural the aboriginal eight weeks.

VIDAZA and REVLIMID are not an accustomed aggregate for analysis of patients with higher-risk MDS.

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Source:

Celgene International Sàrl

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Posted in: Biologic Trial News | Medical Condition News

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Tags: Anemia, Angioedema, Anorexia, Arthralgia, Back Pain, Bone, Bone Marrow, Cancer, Cell, Constipation, Contraception, Cough, Dialysis, Diarrhea, DNA, Dysgeusia, Dysplasia, Epistaxis, Fever, Gene, Headache, Hematology, Hypersensitivity, Hypokalemia, Leukemia, Leukopenia, Liver Disease, Lymphoma, Multiple Myeloma, Muscle, Myeloma, Nausea, Neutropenia, Nursing, Pain, Pharyngitis, Placebo, Platelets, Pregnancy, Protein, Pruritus, Pulmonary Embolism, Revlimid, Semen, Thalidomide, Thrombocytopenia, Thrombosis, Vascular, Vasectomy, Vidaza (Azacitidine), Vomiting



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